Impact of High-Temperature Exposure on Workers Biological Aging

Background: Occupational heat exposure is an increasing concern as global temperatures rise, with studies suggesting it may accelerate biological aging in workers. This is particularly relevant given that over 2 million workers in high-heat industries may be at risk of adverse health effects due to prolonged exposure.

Method: This was a cross-sectional study involving 300 workers from various high-temperature occupations. Biological age was assessed using epigenetic clock analysis, comparing biological age indicators to chronological age. Statistical analyses included linear regression to adjust for confounding factors such as age, gender, and chronic health conditions.

Results: Workers exposed to high temperatures exhibited a mean biological age that was 5 years older than their chronological age (P<0.01). The study found a 20% increase in the rate of biological aging for each 10 degrees Celsius increase in occupational heat exposure, with evidence of a dose-response relationship.

Conclusion: These findings suggest that high-temperature exposure significantly accelerates biological aging in workers, indicating an urgent need for improved occupational health guidelines and preventive measures. The limitations of this study include its cross-sectional design and reliance on self-reported exposure, warranting further longitudinal studies to strengthen these associations.

Original citation address: https://www.besjournal.com/en/article/doi/10.3967/bes2026.016